Compare Vyvanse (lisdexamfetamine) vs. Provigil (modafinil)

Provigil is a drug approved for the treatment of excessive daytime sleepiness associated with narcolepsy. Provigil has an illegible mechanism of action but is believed to alter histamine, dopamine, other monoamines, and stimulate orexin receptors. On the other hand, Vyvanse is a stimulant medication used to treat ADHD disorder in children, adolescents, and adults, but it can be expensive since it’s only available as a brand name product.

These two drugs are considered medically active for the treatment of narcolepsy. Both drugs are commonly used for cognitive enhancement among business executives and college students. In this post, we’ll compare both drugs and see how they differ.

 

Vyvanse vs. Provigil: Upsides

Vyvanse

• Vyvanse can be used to treat attention-deficit/hyperactivity disorder (ADHD).
• Taking Vyvanse will make you feel more confident in your skills and abilities.
• You’ll probably feel more motivated to exercise and eat healthy foods.
• Vyvanse will help you become way more efficient in your everyday life.
• You’ll experience a noticeable improvement in your career or business.

Provigil

• Provigil (modafinil) has been shown to increase resistance to fatigue and improver mood
• Provigil is available in a cheaper, generic version.
• Modafinil improves motivation, reaction time and vigilance.
• Provigil (modafinil) is useful for decreasing excessive sleepiness in shift work sleep disorder.
• Provigil (modafinil) is also helpful for people whose jobs require them to be alert and active at night.
• Studies have revealed that Modafinil increases and retains cognitive function.
• Users that experience sleep deprivation or have hyper-insomnia find that their mental performance is heightened after using modafinil.

Vyvanse vs. Provigil: Downsides

Vyvanse

• This medicine has the potential for abuse and dependence.
• Vyvanse can slow growth in children and cause weight loss.
• Vyvanse can cause serious side effects on the heart when misused.
• Vyvanse has a negative impact on both mental and physical health when abused.
• Vyvanse causes difficulty in sleeping at night if not taken in the morning.
• Vyvanse is expensive because it’s not available as a generic medication.

Provigil

• Provigil shouldn’t be used for long-term treatment because it inhabits tolerance
• Provigil (modafinil) is not a good choice for those having liver problem.
• Provigil may not be a good option for those taking hormonal contraception.
• Modafinil dehydrates the body; you will drink more water than usual when you use this drug.
• Modafinil acts as an appetite suppressant, which is excellent for people who are trying to lose weight.
• Modafinil may cause you to be ‘wired’ after use, which may cause you to find it hard to sleep at night.

 

Vyvanse vs. Provigil: Uses

Vyvanse

• Vyvanse reduces binge eating,
• Vyvanse improves ADHD symptoms.
• Vyvanse can enhance cognitive functioning in menopausal women.

Provigil

• The FDA approved Provigil for the treatment of narcolepsy.
• Doctors prescribe Provigil as antidepressant augmentation strategies from an off-label perspective.
• Provigil (modafinil) is also approved for the treatment of obstructive sleep apnea (OSA), and shifts work sleep disorder (SWSD).
• Provigil is prescribed for chronic fatigue syndrome, depersonalization disorder, delayed sleep phase syndrome, fibromyalgia, multiple sclerosis, and Parkinson’s disease.

 

Vyvanse vs. Provigil: Dosage forms

Vyvanse

• Vyvanse recommended dose for the treatment of ADHD in adults is 30 mg taken once a day in the morning.
• Vyvanse recommended dose for the treatment of binge eating in an adult is 50 to 70 mg daily.
• The maximum dose per day is 70 mg.
• Vyvanse can be taken in the morning with or without food but avoid afternoon doses because of the potential for insomnia.
• You can administer Vyvanse by swallowing the whole capsules or mixing the entire contents with yogurt, water, or orange juice.

Provigil

• Provigil dose should be taken in the morning or as directed by your doctor. The standard Provigil (modafinil) dose are between 100 – 200 mg.
• The recommends prescribed dosage for any disorders is one 200 mg of Modafinil each day.
• 400 mg of Provigil dose per day seen to be safe and well tolerated for some people.
• Limit your Modafinil intake to three times a week for example if you are using Modafinil for short-term.
• Modafinil appears to be safe for long-term at moderate (100-200 mg) daily dosages.

 

Vyvanse vs. Provigil: Cost

Vyvanse

• The most common version of Vyvanse will cost around $301.48, 18% off the average retail price of $371.01.

Provigil

• The most common version of modafinil will cost around $36.61, 95% off the average retail price of $776.00.

 

Vyvanse vs. Provigil: Safety Precautions

Vyvanse

• Keep the drug in a dry and cool place where others cannot get to it.
• Vyvanse is a drug of abuse, and you should be aware if anyone is misusing your medicine or without a prescription.

Provigil

• Keep track of your medicine.
• Store Provigil at room temperature away from heat, moisture, and light.

Vyvanse vs. Provigil: Possible Side Effects

Vyvanse

• Difficulty falling asleep, Sweating
• Stomach pain, Vomiting, Nausea
• Decreased appetite, Weight loss
• Excessive sweating, Rapid heart rate
• Seizures, Chest pain, Uncontrollable shaking
• Swelling of face, tongue, lips, or mouth
• Dizziness, Dry mouth, Increased blood pressure
• Blue fingers or toes, Numbness, Diarrhea

 

Call your physician if you have severe side effects of Vyvanse including:

• Blurred vision, Irregular heartbeat
• Rapid or unexplained weight loss
• A change in sexual ability or interest
• Uncontrolled movements, Muscle twitching or shaking
• Skin color change, Sensitivity to temperature
• Behavior changes such as aggression, agitation, depression, mood swings, hallucinations, suicidal thoughts or attempts, abnormal thoughts or behavior

 

Provigil

• Flu symptoms
• Palpitation, Headache, Dizziness;
• Throat inflammation, Chest pain
• Skin rash or hives, Peeling or Blisters
• Nausea, diarrhea, upset stomach
• Mouth sores, Trouble in swallowing
• Shortness of breath, Fever
• Burning/tingling sensation
• Abnormal liver function
• Dilation of blood vessels
• Feeling nervous or anxious
• Lung disorder, Loss of appetite
• Sleep problems (insomnia)
• Yellowing of the eyes or skin
• Swelling in your face, tongue, lips, or throat

 

Call your physician if you have severe side effects of Vyvanse including:

• Anxiety, Depression, Suicidal actions or thoughts
• Unusual thoughts or behavior, Hallucinations, Aggression, Being more active or talkative than usual
• Trouble breathing, Uneven heartbeats
• Any skin rash, no matter how minor or small you think it might be.